Wonderful to hear from you! I have several files that I'd like to attach to an email to you. I'll try your address listed online. But, first I'll contact you and once you reply - I'll send the files.
I feel pretty good about your Isaac being the brother to my John. I have discovered that my John did not die as early as I thought. He died bet 1856-60 although he does not appear on the 1850 or 1860 census with his wife and children in Guernsey and Noble Cos, OH he is mentioned as an heir in his father's estate in 1856 and living in California. It's possible that he and Elizabeth Miller may have divorced but I don't have any proof.