I have a Mary Margaret Weatherby who married Mark McAfee in Athens in 1818.She was b. 1799 in Cape May NJ, daughter of John Wesley Weatherby and Elizabeth Lacy.John is listed on the 1850 census living with Mark and Mary.
On the 1830 census in Carthage, Athens OH is a John McLain age 20-30 living next door to Isaac Weatherby.
John and Elizabeth Weatherby had a son named Isaac, b. 1790 in Cape May NJ.He married Elizabeth Kennedy.