Danny, I just ran across this posting. I have been dealing with 4 families in Amherst County, Virginia when I accidentally found some Maryland roots.
In the early 1750's Susannah Lee married John Bowling (widow) in St. Mary's County, Maryland.Susannah was the daughter of Thomas and Mary Lee and cousin's to the Lee's of stafford VA where General Robert E. Lee would stem. John Bowling was the son of Edmund Bowling and who was married before and had at least three children, Edmund, John, and Mary.Susannah and John Bowling had at least one son, James.John died and left guardianship to all his children to Susannah.Susannah Lee Bowling married second Notley Warren Maddox, son of Notley Maddox and Mary Warren of St. Mary's County, Maryland.Notley and Susannah Lee Bowling Maddox had Judah Warren Maddox and a son born after Notley died.That son was named Notley Warren Maddox after his father.Susannah Lee Bowling Maddox married a third time to a widow by the name of John Cartwright.In 1769 John packed his family and associated members (from previous marriages) and moved west to the mountains in VA to a newly created county formed from Albemarle County called Amherst.In an area called Rose's Mill John Cartwright brought property from an Ambrose Jones.Ambrose sold John Cartwright land next to holding by Thomas Jefferson.Rose's Mill sits on the Piney River that is now (as of 1807) the dividing point of Amherst and Nelson County VA.The property was also neighbored by in addition to Thomas Jefferson; Joseph Dillard, Thomas Wortham, George Gillaspie, and Robert Rose. Since John Cartwright had brought everyone with him they started marrying the neighbors children.James Bowling married Lettice Moore Gillaspie daughter of George Gillaspie (who would be overseer of Rose's mill), Notley Warren Maddox married Frances "Fanny" Dillard daughter of Joseph Dillard, Edmund Bowling now called Edward was already married when he got to Amherst, and Judah "Judith" Warren Maddox married George Wortham son of Thomas William and Elizabeth Taliaferro Wortham.
George Wortham (b. 1760) and Judith Warren Maddox (b.1759) had Nancy Wortham who married Edmund Andrew Massie, Notley Wortham who married his cousin from Culpeper Susannah Maddox, Mary Wortham who married William Goode, Sarah "Sally" Wortham who married John Cash, and George Wortham who married but I don't have record of it. I believe the sibling you mention are from the second George and not the first (Judith Warren Maddox would have been in her 50's when Elizabeth was born). All these people (except for James Bowling) picked up and moved to Georgia shortly after 1800. Two returned John Maddox and Edmund Massie to Amherst.
Hope this helps --
PS -- I come from all the families mentioned.They heavily intermarried.In fact my grandparents were first cousins.