| Name | Sex | Birth date | Birth location | Death date | Death location | Spouse | Marriage date | Marriage location |
| Sayre, William | Male | 1514 | Hinwick, Bedford, England | 1564 | Hinwick, Bedford, England | Squire, Alice | Abt. 1528 | Bedfordshire, England |
| Sayre, William | Male | Abt. 1535 | Hinwick, Bedford, England | Bef. 1581 | Leighton Buzzard, Bedford, England | Squyer, Elizabeth | Abt. 1558 | |
| Scargill, Agnes | Female | | | | | Calverley, Thomas | | |
| Schwarenger, Widow | Female | | | | | Farnsworth, Reuben | | Plymouth, IN |
| Scot, William | Male | | | | | Calverley, Daughter | | |
| SCOTLAND, Agnes | Female | | | | | | | |
| SCOTLAND, Elizabeth | Female | | | | | | | |
| SCOTLAND, Isobel | Female | | | | | | | |
| SCOTLAND, Janet | Female | | | | | HARROWER, John | Abt. 1702 | Clackmannan, Clack, Scotland |
| SCOTLAND, John | Male | | | | | | | |
| SCOTLAND, John | Male | Abt. 1651 | Clackmannan, Clack, Scotland | | | RID, Bessie | July 29, 1676 | Clackmannan, Clack, Scotland |
| SCOTLAND, Margaret | Female | | | | | | | |
| SCOTLAND, Mary | Female | | | | | | | |
| Scotland, Matilda Of | Female | 1079 | | May 01, 1118 | | Henry, I Beauclerc of England | November 11, 1100 | |
| SCOTLAND, Thomas | Male | | | | | | | |
| Scott, Elizabeth | Female | | | | | Loomis, John | Bet. February 03, 1646/47 - February 1647/48 | Windsor, CT |
| Scranton, Thomas | Male | | | | | Dudley, Deborah | 1664 | Stonington, New London, Connecticut |
| Scripture, Deborah | Female | | | | | Whitcomb, Jonathan | September 04, 1710 | Concord, MA |
| SCROPE, Adrian | Male | | | | | Waller, Mary | | |
| Scrope, Henry | Male | | | | | Conyers, Margaret | | |
| Scruggs, Polly | Female | | | | | Gilbert, John | 1796 | |
| Scudamore, Clement | Male | | | | | Page, Barbara | | |
| Sedgwick, Prudence | Female | | | | | Kellogg, Amos | May 27, 1747 | |
| Sefton, ??? | Male | | | | | Bold, Elizabeth | Abt. 1461 | |
| Selbee, Susan | Female | Abt. 1586 | England | Bet. January 20, 1657/58 - January 1658/59 | Boston, Suffolk, Massachusetts | Blott, Robert | August 31, 1609 | Harrold, Bedford, England |
| Selby, Mary | Female | 1564 | Of Yorkshire, England | | | Bere, John | | |
| Selby, Robert | Male | 1538 | Eng | | | ??? | | |
| Selden, Thomas | Male | | | | | Lewis, Felix | 1675 | Hadley, Hampshire, Massachusetts |
| Seldon, Samuel | Male | | | | | Dudley, Elizabeth | | |
| Sevors, Joseph | Male | | | | | Reed, Mary | October 13, 1700 | |
| Sexton, George | Male | | | | | Spencer, Hannah | | |
| Seymour, Alice | Female | | | | | De Neville, Thomas | Abt. 1421 | Of |
| Seymour, George | Male | | | | | Vessey, Susan | August 02, 1585 | Little Baddow, Essex, England |
| Seymour, Mary | Female | | | | | Langton, John | December 20, 1655 | |
| Shan, Chloe | Female | | | | | Stacy, John | | |
| Shan, Rufus | Male | | | | | Stacy, Salome | | |
| Shanks, Joseph | Male | | | | | Gilbert, Martha Eliza | June 08, 1922 | |
| Shanks, Mary | Female | | | | | Farnsworth, Reuben | | |
| Sharp, Abigail | Female | | | | | Jeggles, Thomas | October 27, 1647 | |
| Sharp, Agnes | Female | | | | | COOK, John | June 16, 1740 | |
| Sharp, Alexander | Male | Abt. 1655 | | | | Condie, Agnes | Bet. February 16, 1669/70 - February 1670/71 | Clackmannan, Clackmannan, Scotland |
| SHARP, Andrew | Male | | | | | | | |
| SHARP, Andrew | Male | | | | | | | |
| SHARP, Andrew | Male | Abt. 1667 | Clackmannan, Clack, Scotland | Aft. 1711 | | SHARP, Elspeth Elspet | September 28, 1687 | Clackmannan, Clackmannan, Scotland |
| SHARP, Androce | Male | | | | | | | |
| Sharp, David | Male | | | | | Hunter, Elizabeth | April 11, 1830 | |
| SHARP, Elspeth | Female | | | | | | | |
| SHARP, Elspeth Elspet | Female | July 12, 1669 | Clackmannan, Clackmannan, Scotland | Aft. 1711 | | SHARP, Andrew | September 28, 1687 | Clackmannan, Clackmannan, Scotland |
| SHARP, James | Male | | | | | | | |
| Sharp, James | Male | | | | | Condie, Janet | | |