Don't really know who your Nancy McDaniel/McDonald is but saw your message and can point you to these pages to help puzzle out Maury co, Giles co TN and some Kentucky McDONALDS. This particular family seems to be spread and traveling along the Ohio River.
Perhaps you will be fortunate and find your Nancy already included here.
The information is based on Frank V. McDonald's family book from the 1870s.
It is not unusual to see McDANIEL/McDONALD surnames for the same individual btw.
My own John McDONALD was born in Botetourt Co., Virginia 1756, d. 1807 in Giles Co., Tennessee (record in Maury co, TN). Most of the McDONALDs in early Giles co, TN are related I believe. (His second wife was an Elizabeth Canaday/Kennedy btw, and for some reason after his death the daughters from his second marriage are in the Ohio Falls area.)
His brother William's family seems to be strongly associated with early Bardstown, Kentucky.