A book, "The Annals of Newberry" states that it "began to be settled before 1752,"Thus, your ancestor could be among the early settlers.
On page 107 of that book it is written... "In 1824 Col. Samuel Cannon was elected Sheriff.This clever and good man was descended from the earliest settlers of Newberry.The creek near which he was born, raised and died, was called after one of his ancestors "Canno's Creek."He was a major in Col. Tucker's regiment."
This Samuel is no doubt a great-grandson of the Samuel for whom you search.Good luck.M. Watson