Sofia: I hope you are still reading this forum. Here is recent information I found on my great-great grandfather Pantaleone Appignani. He was born in 1833; he married Giulietta D'Assenzio in 1867.Based on your note, many of the names you mentioned in your posting match what I have found, but they may be a generation later!
If you could tell me the approximate years or dates of birth of the people in your note (your father Pantaleone and who he married, your aunt Giulia and who she married and when, and your grandfather James and his last name and who he married) I can compare with what I have.
Is it possible that your father, Pantaleone or Leo, is the grandson of my great great grandfather Pantaleone Appignani, who married Giulietta, and his sister's name was Giulia, named after Pantaleone #1's wife? And, their father's name (your grandfather) was James Appignani, who was another son of Pantaleone and Giulia?
I have not been able to find information farther back than Pantaleone, born in 1833, but would like to see where your grandfather James fits in. here is what I have on the children of Pantaleone Appignani, my Great-Great Grandfather, in this order:
Concetta (My great Grandmother) Born 1863 Brigida Born 1866 Luigi 1872 Sofia 1874 Annina 1876 Attilio 1878 Arnaldo 1881 Sinegrande 1885
I suspect there must have been more children, because they were born every few years and there is a time lag of about 6 years between Brigida and Luigi.Perhaps that's where your grandfather James fits in?