I'm an Applegate descendant, though haven't connected your branch to mine as of yet.I did run across this tonight and thought it might interest you:It's from "Christian Advocate" 8 June 1882; 57; 23.It reads:
"Mrs Elizabeth Drake Applegate was born May 10, 1801 in Washington County, PA and died at Franklin, Johnson County, Ind. May 19, 1882, aged 81 years and 19 days.When she was one year old her father moved to Warren County, O.In 1819 she was married to Bartholomew Applegate, and in 1821 they went to his home in Ocean (then part of Monmouth) County, NJ.In 1832 they moved to Johnson County, Ind., near Edinburgh.In 1854 her husband died, leaving her with several small children.In 1869 she moved to Franklin.In early life she joined the Baptist Church, and lived a consisten member until about 1836, when, with her husband, she united with the Methodist Episcopal Church, and lived a consistent member.They always welcomed the Methodist itinerants.During her last sickness she never expressed a doubt of her acceptance with God.During her lucid intervals she expressed no desire to recover.She said she had more and greater ties in heaven than on earth.She had thirteen children, two dying in infancy and eleven growing to maturity, most of whom are members of some Christian church.She was a devoted and loving wife and mother, and a submissive widow.We mourn not as those who have no hope. W. L. A."
Sorry it doesn't say anything on her parents, but thought maybe there was something to be gleaned from it anyway.