I have Margaret and the brothers you list as 5 of the 13 children of George Brewer b. abt 1775 NC and Jane Butler b. abt. 1780.
George Brewer was one of 35 son and 3 daughters, by 3 wives, of Lanier Brewer of Brunswick, Virginia. Sorry I don't have a lot on the Brewer's as they are not my line. A couple of our Wilson girls married into the family in Wayne Co. TN so I have some limited knowledge.