I can see from your other messages that you have looked in "The Doty-Doten Family in America" book. My Henry is #3377. The line of descent is Edward/Samuel/Isaac/Micajah. He settled in Belmont Co., Ohio. His brother John Doty settled in Marshall Co., WV across the Ohio river.
I'm aware of your branch(es) in Washington & Greene Co.s, (I have some ancestors from those Co.s), but I have not done any research on them. The only other family in the area that I'm aware of is John & Peter Doty who settled in Brooke Co., WV and then moving on to Knox & Morrow Co.s, OH. They are descended from Edward/Samuel/Edward/John.
Strange that some of your Washington & Greene Co.s Dotys ended up in Knox Co. also!I know your research is also not helped by those PA Co.s not having any County level marriage records until 1880s...The only other thing I can add is that some of your Dotys ended up in Monongalia Co. WV and that I helped somebody trying to find out more about a William H. H. Doty.