Drusilla is a very interesting name for me. My John JAMES/Lavinia SMITH 1802 marriage saw a daughter Drusilla born 1816. There were 2-3 other Drusillas in the downline. It must have been a family name and I don't think Drusilla was that big a name.
Maybe so, maybe not. I think is an important name though, possibly a sister, mother or grandmother to my John.
Are you aware of any DNA studies in your JAMES line?