I am related to a Cain family from Nelson Co and Grayson Co KY. The surname spelling can be variable - Cain, Caine, Kain, Kane, Kean, etc. We have been able to work out which of these Kentucky families are related & which are not by Y-DNA carried by the direct male line. As a male line Kean this is something for you to think about. With 213 members of the Cain DNA project at www.familytreedna.com/public/Cain-Caine you have a good chance of getting more information this way.