Mackie/Gladstone Scotland and England

Interested in Ivie Mackie b 1806 and Agnes H. Gladstone b ca 1814. Agnes Halliday Gladstone was born in or near Castle Douglas, Kelton, Scotland, daughter of John Gladstone and Elizabeth Muir. Ivie Mackie was a wine and spirit merchant and had a business Mackie and Gladstone with Agnes' brothers...locations in Birmingham, Liverpool, Manchester, Dublin, etc. They lived in Manchester in 1861...death records for Ivie (1873) and Agnes (1878) at Auchencairn, Rerrick, Kirkcudbrighshire, Scotland...