Lewis Massie, 1850 Lawrence Co. OH

My grandfather was F. Thomas Massie(b MO 1900), his father Lewis H. (b OH 1868), his father Anderson (b OH, 1831), his father Lewis (b VA, 1803 ?), The problem I'm seeking help with is the last Lewis- found in the 1850 Law. Co. OH census with wife Sarah (b VA 1810) together with Anderson and all his siblings (Henderson, Elihu, Jams P., Mary, John, Alex and Stephen). This Lewis is not in the 1860 census, but there is another Lewis, married to a Sarah, but older and with a completely different set of children, so I don't think its the same one (maybe cousins ?)! My Lewis'children are all born in OH, with the first in 1829. However, I can't find him in the 1840 or 1830 census for OH. . Does anyone know anything about this Lewis (1850)? Thanks for any help.