This Luke may have been a son of Luke Wiley who died and his estate probated in Henry County, KY in 1810 Henry County, KY, Cyrus Wiley was thought to be a nephew of Luke Wiley dec'd. most of these children wound up in Posey County, Indiana, Luke died in Perry County, his widow was Minerva.
Court Orders; Henry County, KY June-August Court, 1810
Lytle Wiley, bound to Luke Short to learn the mastery of Saddle making. (was living in Posey County, IN in 1850)
James Wiley, bound to George Cardwell to learn the art of Wheelwright.
Priscilla Wiley was bound to Thomas Ellison to learn the art of housewifery.
William Wiley, bound to Hause McClellems to learn the art of tailoring
(This Luke Wiley seems to fit the age of the one in 1840 Perry, IN, if so, his father Luke Wiley was likely born in Maryland and died probably in Henry County, KY before 1810, note: Luke Wiley Jr. was probably too young to be apprenticed (bound out), being under 10 years of age)
March Court, 1810, Henry County, KY Benjamin Wiley appointed guardian for Nancy, Litle, Luke, James, Priscilla and Mary Wiley, infant heirs & representives of Luke Wiley dec'd.; Benjamin Wiley, James Wiley & Joseph DePuy entered into bond.
But then the name "Luke" was very common in that family from Baltimore, MD to Lincoln County, KY 1770's